It looks like after decades, ReMapKey (from the Windows 2000 and 20023 Resource Kits, see If you miss having the Caps Lock button on your #Chromebook… (via: Google Chrome – Google+)) got a successor:
[Wayback/Archive] PowerToys Keyboard Manager utility for Windows | Microsoft Docs:
The PowerToys Keyboard Manager enables you to redefine keys on your keyboard.
For example, you can exchange the letter A for the letter B on your keyboard. When you press the A key, a
B
will display.…
You can also exchange shortcut key combinations. For example: The shortcut key Ctrl+C will copy text in Microsoft Word. With PowerToys Keyboard Manager utility, you can exchange that shortcut for ⊞ Win+C. Now, ⊞ Win+C will copy text. If you do not specify a targeted application in PowerToys Keyboard Manager, the shortcut exchange will be applied globally across Windows.
PowerToys Keyboard Manager must be enabled (with PowerToys running in the background) for remapped keys and shortcuts to be applied. If PowerToys is not running, key remapping will no longer be applied.
The real kicker however, is that the new PowerToys Keyboard Manager can be application specific: